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     Thippali (Kabab-chini, Java peppercorn) pdf
   
  Botanical Name(s): Thippali
Family Name: Piperaceae
Kingdom: Plantae
Division: Magnoliophyta
Class: Magnoliopsida
Order: Piperales
Family: Piperaceae
Genus: Piper
Species: P. longum
Popular Name(s): Indian Thippali, Indonesian Thippali, Dried Catkins, Pippali, Pipal, Tippli, Pihal, Javanese Thippali
Parts Used: Fruit, Root and Stem.
Habitat: Mostly deciduous to evergreen forests.
Description
Thippali is a slender aromatic climber, with a large perennial woody root and jointed stems thickening at the nodes. The dark, dentate leaves are ovate and heart-shaped, about 2 to 3 inches in length, with broad rounded lobes at the base. The flowers are monoceous and male and female flowers are borne on different plants. The fruits are ovoid, yellowish-orange, minute, and drupe around 1 inch in diameter. The spikes are red when ripe and turn to black on drying. The plant bears flowers in rains and fruits in early winters. The herb is cultivated in Assam, Tamil Nadu and Andhra Pradesh in India, Malaysia, Indonesia, Singapore, Sri Lanka and South Asian regions. Thippali is also known as pipal and pipar in Hindi, hippali in Kannada, kandanthippili in Tamil, pippali rasayana, magadhi, kana and ushana in Sanskrit, pippal in Gujarati and pepe di Marisa in Italian.
 
About the plant
Thippali belongs to the family of black pepper, Piperaceae. The plant is a slender, glabrous, climber or creeping shrub that spreads on ground striking roots at each node. It produces two distinct dimorphic branches – vegetative main branches that creep on ground; and erect growing reproductive axillary branches. The plant flowers through out the year and is dioecious in nature with the male and female flowers produced on different plants. Inflorescence is spike; about 35 millimetres long and 5 millimetres thick, composed of large numbers of minute grayish green or darker grey fruits, which, together with the bracts that support them, are embedded in the elongated axis; and the the whole being covered with greyish dust.
 
Cultivation
Soil and climate

Thippali grows well in organic matter rich fertile, well-drained soils. Laterite soils with high organic matter content and moisture holding capacity are also suitable for the cultivation. Optimum elevation for its cultivation is between 100 to 1000 m and higher elevations are not conducive to high yields. Partial shade of 20-25 per cent shade intensity is found to be the optimum.

Varieties

Different types of thippali - cheemathippali, cheru thippali, vanthippali, kattu thippali are identified. Cheemathipali is a common cultivated clone of Kerala. Viswam is a high yielding variety of thippali released by the Kerala Agricultural University for commercial cultivation.

Nursery preparation

Thippali is propagated by rooted vine cuttings or suckers. Vine cuttings of 3-5 nodes are planted in polybags filled with top soil, farm yard manure and sand in the ratio 1:1:1 during March-April. Normal irrigation may be given on alternate days. Excess moisture in the nursery can cause Phytophthora wilt. To avoid mealy-bug attack on roots, 10 per cent DP of any organo-phosphorus insecticide is to be mixed with the potting mixture. Cuttings will root in two weeks and can be transplanted to the main field after one month.

Land preparation and sowing

The field should be ploughed two to three times and levelled properly. Raised beds of size 3m x2.5 m are prepared and pits are dug at a distance of 60 cm x 60 cm. Dried cow dung or farmyard manure at the rate of 100 g per pit is applied and mixed with soil. Application of chemical fertilizers is not practiced commonly. Plant two rooted cuttings or suckers per pit in the main field soon after the onset of monsoon.
 
Main constituents
The chief constituents of thippali are about six per cent of piperine and one per cent of volatile oil. Other constituents are a pungent resin namely chavicin and starch. Compounds like piper longuminine, cetostearol, methyl piperate and a series of piperine retrofractamides have also been reported.
 
Habitat
It is considered a native of South Asia and is found both wild as well as cultivated, throughout the hotter parts of India from central to the north-eastern Himalayas. The herb also grows wild in Malaysia, Singapore, Bhutan, Myanmar and elsewhere.
 
What Ayurveda has to say on Thippali:
yeloball It suppresses the influence of peta body type and enhances the role of vata and kapha body types. This restores balance among the basic body types.
yeloball Its pungent taste is believed by Ayurveda to treat any kind of infection.
yeloball Its treats asthma by clearing the mucus which get stuck in the pathways of breathing.
yeloball It clears pathways from where food passes and gets converted in to waste products. In this way, constipation is addressed.
yeloball It is believed to treat Sinus problem and nervous weakness too.
yeloball Oil prepared from extracts of the fruits of this herb are applied on the wounds to treat them.
yeloball The roots are dried and powdered. Intake of this powder in normal dosage treats respiratory, digestive and urinary tract complaints.
 
Thippali in Other Languages
Gujarati: Lindi pipar (roots are known as Ganthoda)

Marathi: Pippali

Bengali: Pipul

Kannada: Hippali

Tamil & Malayalam: Tippali

Hindi Name : Pepper

Sanskrit Name : Pippali
 
Uses & Benefits of Thippali
yeloball Thippali helps in expelling out the mucus accumulated in the respiratory tract.
yeloball It strengthens the nervous system, improves the gastrointestinal condition and normalizes the peristaltic movements.
yeloball The herb serves as a good digestive agent.
yeloball Its oil and paste is applied on wounds and skin-related ailments.
yeloball Thippali helps in suppressing pain and reducing inflammation.
yeloball The herb helps maintain the normalcy of the digestive tract and tones up the urinary tract.
yeloball Its fruits are used for respiratory tract diseases like cough, bronchitis and asthma.
yeloball It benefits in anorexia, indigestion, flatulence, abdominal pain, hyperacidity, piles, paralysis of the tongue, diarrhea, cholera, chronic malaria, viral hepatitis, diseases of the spleen and tumors.
yeloball It is given with amalaki, to treat anemia.
yeloball The decoction of the plant is used in sciatica and hemiplegia.
yeloball The herb is mixed with honey to control hiccups.
yeloball Thippali is used as an aphrodisiac, since it boosts the reproductive system.
yeloball It is used as a sedative in insomnia and epilepsy.
yeloball The infusion of the herb’s root is used after childbirth, to induce the expulsion of the placenta.
 
Medicinal and pharmacological activities
Immunomodulatory activity: Tests such as haemagglutination titre (HA), macrophage migration index (MMI) and phagocytic indeJ (PI) in mice have demonstrated the immunostimulatory action of Thippali fruits to be both specific and non-specific. The effect was more prominent at lower doses (225 mg/kg) and was marginally reduced when the dose was increased," In another study, it was found to offer protection against externally induced stress,' A famous Ayurvedic preparation containing Thippali, Pippali Rasayana, was tested in mice infected with Giardia lamblia and found to produce significant activation of macro phages, as shown by an increased MMI and phagocytic activity.

Stimulant effects: Isolated piperine showed a central stimulant action in frogs, mice, rats and dogs and increased the hypnotic response in mice. It antagonised respiratory depression induced by morphine or pentobarbitone in anaesthetised dogs anda petroleum ether extract of the fruits antagonised morphine-induced respiratory depression in mice, A comparative study conducted with piperine and nalorphine,for effects against morphine-induced respiratory depression and analgesia, found that both reversed respiratory depression but, unlike nalorphine, piperine did not antagonise morphine-induced analgesia in rats,

Antiasthmatic activity: Studies have been carried out to validate the traditional claims of Ayurveda for antiasthmatic activity of Thippali. An extract of the fruits in milk reduced passive cutaneous anaphylaxis in rats and protected guinea pigs against antigen-induced bronchospasm.

Bio-availability enhancement: Piperine has been shown to enhance the bio-availability of structurally and therapeutically diverse drugs, possibly by modulating membrane dynamics, due to its easy partitioning and increasing permeability.The effect of Trikatu', a compound Ayurvedic preparation containing Thippali as one of the major ingredients, was tested in combination with other drugs. The study reported that Trikatu' increased their bio-availability either by promoting rapid absorption from the gastrointestinal tract or by protecting the drug from being metabolised during its first passage through the liver after being absorbed, or by combination of both mechanisms.

Hepatoprotective activity:
Piperine was evaluated and found to exert significant protection against tertiary butyl hydroperoxide and carbon tetrachloride­induced hepatotoxicity, by reducing both in vitro and in vivo lipid peroxidation. A fruit extract was assessed in rodents for its hepatoprotective action against CCL,­induced acute, chronic and reversible damage and chronic irreversible damage, using morphological, biochemical and histopathological assessment parameters. The extract improves the regeneration process by restricting fibrosis, but offered no protection against acute damage or against cirrhotic changes.

Hypocholesterolaemic activity: Methyl piperine significantly inhibited the elevation
of total serum cholesterol, and the total cholesterol to HDL-cholesterol ratio, in rats fed with a high cholesterol diet. The unsaponifiable fraction of the oil of Thippali also significantly decreased total serum cholesterol and hepatic cholesterol in hypercholesterolaemic mice.

Antiinflammatory activity: A marked antiinflammatory activity of a decoction of P. longum fruits has been reported using carrageenan-induced rat oedema.

Antiamoebic activity: The fruits were tested for their efficacy against Entamoeba histolytica in vitro and experimental caecal amoebiasis in vivo. Both the ethanolic extract and isolated piperine produced an improvement of 90% and 40% respectively, in rats with caecal amoebiasis.

Antibacterial activity: The essential oil of P. longum showed antibacterial action against a number of bacterial strains32,33 although a 50% ethanolic extract of the fruits did not show any effect.3' Piperlonguminine was found to have potent activity against Bacillus subtilis while piperine was more effective against Staphylococcus aureus.
 
The oil contains:
yeloball Piperine
yeloball Pipalartine
yeloball Piplasterol
yeloball Sesamin
 
Quality Assurance
As we believe in providing quality products that are close to nature, we conduct various stringent quality tests under the supervision of the experts. These tests are performed with due care from the very initial stage of procurement of the products to the final stage of delivery to the end users.
 

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thippili plant

 

 

 


 


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